Articles tagged with “master-protocol”

Adaptive Trial Design: A Guide to Flexible Clinical Trials

An in-depth guide to adaptive trial design. Learn how prespecified changes based on interim data can make clinical trials more efficient and ethical.

45 min read

11/22/2025

adaptive trial design clinical trials master protocol platform trials biostatistics interim analysis fda guidance sample size re-estimation

What is a Clinical Trial Protocol? A Guide to Its Design

A guide to the clinical trial protocol. Learn its core components, importance in research, and how to manage complexity and amendments for successful trials.

55 min read

11/18/2025

clinical trial protocol clinical research protocol design good clinical practice ich-gcp protocol amendment regulatory compliance drug development master protocol