Dotmatics Consulting & Integration for Life Sciences
Empowering pharmaceutical and life science organizations with cutting-edge AI solutions.
Services Across the Dotmatics Portfolio
Luma Platform Implementation
Plan and roll out the Dotmatics Luma scientific intelligence platform. Registration, assay, ELN, and search unified on a cloud-native data fabric with governed APIs for AI and analytics.
Legacy Studies and Elements Migration
Move from on-prem Studies, Browser, and Bioregister into Luma or a hybrid model. We inventory templates, SAR queries, and saved reports, and migrate them with no data loss.
GraphPad Prism Standardization
Organization-wide Prism rollout with template libraries, validated ELN-to-Prism pipelines, and figure governance so statistical plots are regulatory-grade, not ad-hoc.
SnapGene and Geneious Enterprise
Scale molecular biology tooling across discovery and biologics groups. API-driven sequence governance, construct traceability, and integration with Benchling, Veeva Vault, and Luma.
LabArchives ELN Deployment
Roll out LabArchives for translational, discovery, and academic-linked teams with templated entries, SOP-aligned workflows, and controlled sharing into Vault and SharePoint.
IDBS E-WorkBook and Polar
Modernize IDBS E-WorkBook footprints, preserve Activity Builder workflows, and retain IDBS Polar for bioprocess. Phased migration to Luma without disrupting active GxP studies.
Why Dotmatics Matters for Pharma R&D
Dotmatics has consolidated much of the scientific informatics market through acquisitions including GraphPad, SnapGene, Geneious, LabArchives, IDBS, and OMIQ — see the Dotmatics news archive. For pharma IT leaders, this means a single vendor can supply medicinal chemistry registration, biology ELN, statistical publishing, bioprocess development, and flow cytometry — reducing license sprawl and giving one governed data model across R&D.
A Unified Data Fabric with Luma
The strategic center of the modern Dotmatics stack is Luma — a cloud-native platform unifying registration, assay, and ELN data under a shared ontology with a governed API layer. We help customers treat Luma as the R&D system of record, feeding downstream analytics in Databricks and Snowflake, and exposing data to AI agents in a compliant way.
Built for Regulated Environments
Dotmatics applications provide audit trail, e-signature, and access control features aligned with 21 CFR Part 11 and EU GMP Annex 11. We layer a validated configuration on top using ISPE GAMP 5 methodology so the platform is inspection-ready from day one — see our Dotmatics compliance and validation service for the full approach.
Core Capabilities We Deliver on Dotmatics
Registration & Compound Management
Small molecule, biologics, and mixture registration with canonical structure handling, salt/parent logic, and lot-level traceability. Migration from legacy Bioregister, ChemAxon, or custom Oracle registries with zero compound identity loss.
Learn moreAssay Data Management
Standardized assay definitions, IC50 and dose-response curve fitting, and SAR triage views. Integration with plate readers, HCS systems, and third-party CROs through validated file and API pipelines into Luma or Elements.
Learn moreElectronic Lab Notebook
LabArchives and Luma ELN deployments with templated experiments, controlled vocabularies, e-signature workflows, and enforced review/approval cycles that meet 21 CFR Part 11 and EU GMP Annex 11 expectations.
Learn moreBiologics & Sequence Science
Geneious Biologics for antibody and therapeutic protein pipelines, SnapGene cloning workflows standardized across sites, and sequence governance connected to Benchling, Vault RIM, and analytics layers for full biologics lineage.
Learn moreAnalytics & Statistical Publishing
Enterprise-scale GraphPad Prism with validated template libraries, ELN-driven data ingestion, and figure review workflows so regulatory-grade plots move straight from scientist to submission without manual re-work.
Learn moreAI & Scientific Intelligence
LLM-powered assistants connected to Luma via MCP, natural-language SAR triage, ELN retrieval, and automated QC anomaly detection — all with read-mostly, audited access that respects your role-based security model.
Learn moreUse Cases We Build on Dotmatics
Medicinal Chemistry SAR Triage
Weekly SAR review automated with Luma queries and AI-generated summaries of new compounds, property alerts, and off-target risk flags.
Biologics Lead Discovery
Antibody pipeline management spanning Geneious Biologics, Dotmatics registration, and Benchling — with one governed lineage from construct to candidate.
Assay QC Automation
Automated anomaly detection on plate-level assay outputs, flagging bad wells and drift before results reach scientists or management dashboards.
Translational ELN Rollout
LabArchives rollout to translational and biomarker teams with GCP-aware templates, controlled sharing with CROs, and integration into Veeva Vault Clinical.
Prism Standardization
Global template library for dose-response, survival, and comparative statistical plots so figures meet the same standard from bench to submission.
Bioprocess Data Harmonization
IDBS Polar connected to Luma and lakehouse analytics for cross-program bioprocess reporting and tech-transfer packages ready for FDA and EMA review.
Our Engagement Model for Dotmatics Programs
We structure every Dotmatics engagement around three truths: R&D informatics programs fail when scope is too big, when validation is bolted on at the end, and when scientists are not involved early. Our engagement model fixes all three. Work ships in quarterly slices, GAMP 5 validation is embedded from discovery, and a scientist champion is identified per workstream before kickoff.
Discovery & Roadmap
Two to four week sprint to map current state, scientific priorities, integration surface, and validation scope. Output is a prioritized roadmap with cost ranges.
Iterative Delivery
Configuration, integration, and validation run in parallel quarterly slices. Each slice ships a working capability to real scientists before the next starts.
Operate & Evolve
Hypercare transitioning into managed services: periodic review, quarterly releases, AI agent expansion, and continuous integration with Benchling, Veeva, and ERPs.
Today's business insights
Profitable growth in the AI solutions industry
Our CEO discusses how AI is transforming the pharmaceutical industry and shares key strategies for leveraging AI in drug discovery and development.
More insights on unlock profitable growth in ai solutions
Standards, Regulations, and Guidance We Align To
21 CFR Part 11
FDA electronic records and signatures rule covering audit trails, access control, and record retention. Foundational for any Dotmatics GxP deployment in the US market.
EU GMP Annex 11
European equivalent governing computerized systems used in GMP environments. Required for any Dotmatics deployment supporting EU manufacturing or bioprocess programs.
GAMP 5 Second Edition
ISPE risk-based framework for computerized system validation. We deliver all Dotmatics validation packages aligned to GAMP 5 with category-appropriate rigor per component.
ALCOA+ Data Integrity
MHRA and WHO expanded data integrity principles — Attributable, Legible, Contemporaneous, Original, Accurate plus Complete, Consistent, Enduring, Available. We design ELN and assay workflows around these tenets.
ICH Q9(R1) Risk Management
Quality risk management updated 2023. We use ICH Q9 principles to scope validation effort, prioritize integrations, and justify testing depth for each Dotmatics module.
FDA AI in Drug Development
2025 FDA draft guidance and 2026 guiding principles on use of AI for regulatory decision-making. Critical reference for any AI agent connected to Dotmatics GxP data.
Frequently Asked Questions
Dotmatics is a scientific R&D informatics platform used by more than two million scientists across pharma, biotech, academic, and applied markets. The portfolio combines the Luma scientific intelligence platform with widely adopted applications including GraphPad Prism, SnapGene, Geneious, LabArchives ELN, and the former IDBS E-WorkBook lineage. For regulated life sciences teams, Dotmatics matters because it spans molecular design, assay management, electronic lab notebooks, and downstream analysis in a single governed ecosystem — which is exactly where R&D data quality and compliance risk concentrate.
We deliver end-to-end services across planning, configuration, integration, validation, and operations. Our team helps you scope Luma registration, assay, and ELN workflows, map data models to your existing compound and biologics lineage, and build integrations to Benchling, Veeva Vault, SAP, LIMS platforms, and data lakes on Databricks or Snowflake. We also layer AI agents on top using the Model Context Protocol (MCP) so scientists can query structure-activity data, generate Prism-ready tables, and retrieve ELN experiments in natural language.
We support the full modern Dotmatics stack: the Luma platform, Elements registration and assay apps, GraphPad Prism for statistical analysis, SnapGene for molecular biology, Geneious Prime and Biologics for sequence analysis, LabArchives ELN, and the IDBS Polar bioprocess platform. We also maintain coverage of the legacy Bioregister, Browser, and Studies modules so customers can plan migration to Luma on a realistic timeline.
The most common integrations we build are: (1) Dotmatics registration to Benchling or Revvity Signals for scientists standardized on different ELNs across divisions; (2) ELN and assay data flow into Veeva Vault RIM for regulatory submissions; (3) reference data exchange with LabWare LIMS or STARLIMS; (4) compound and assay data into enterprise lakehouses on Databricks; and (5) procurement, inventory, and invoicing sync with SAP or Oracle ERP. We use the Luma and Elements developer APIs as the primary integration surface.
Yes. Luma is the modern cloud-native layer announced by Dotmatics to unify data across the portfolio, and we treat it as the strategic target for most customers. We help teams plan Luma adoption, migrate legacy registration and assay databases, connect Prism, SnapGene, Geneious, and LabArchives ELN to Luma, and build custom apps on the Luma data fabric. For accounts that still rely on on-premise Elements or the legacy Studies cluster, we run a pragmatic hybrid program that avoids a risky big-bang migration.
All three serve overlapping R&D informatics needs but have different strengths. Benchling is a cloud-first ELN and biology-focused registration suite favored by biotech startups. Revvity Signals Notebook and Signals Research Suite are strong on chemistry and analytics. Dotmatics differentiates with the breadth of applications — Prism, SnapGene, Geneious, and IDBS Polar bioprocess all under one roof — and with deep small-molecule chemistry registration heritage. For large pharma with heterogeneous R&D portfolios, Dotmatics often wins because one vendor can cover medicinal chemistry, biologics, bioprocess, and statistical publishing, reducing license sprawl and integration overhead.
Yes. IDBS was acquired by Dotmatics and the E-WorkBook customer base is now being modernized onto the Luma platform over multiple release cycles. We help customers inventory their existing E-WorkBook templates, spreadsheet-based experiments, recipe forms, and Activity Builder workflows, then map them to Luma ELN or LabArchives equivalents. For bioprocess teams, we retain the IDBS Polar footprint and integrate it with Luma for cross-program reporting. Migration always includes a 21 CFR Part 11 validation refresh so historical records retain their e-signature and audit trail integrity.
A focused rollout of one application — for example, LabArchives ELN for a single research site, or GraphPad Prism standardization across analytical chemistry — takes 8 to 14 weeks from kickoff to go-live. A Luma registration and assay program spanning compound management, screening data, and a biologics registry typically runs 6 to 9 months, including validation. A full legacy IDBS E-WorkBook modernization or cross-site harmonization is a multi-quarter program. We always structure work in shippable slices so the first scientists are productive within the first quarter, rather than waiting for a single cutover.
Dotmatics applications provide the technical controls required by 21 CFR Part 11 — audit trails, electronic signatures, access controls, and record retention — but compliance is always a shared responsibility. Vendors cannot validate your specific configuration, integrations, or SOPs for you. We perform a full ISPE GAMP 5 (Second Edition) validation: URS, functional and configuration specs, risk assessment, IQ/OQ/PQ test scripts, traceability matrix, and a validation summary report. We also produce the supplier assessment and periodic review artifacts that FDA and EMA inspectors look for.
AI in scientific R&D is moving from pilot to production quickly — see the FDA AI in medical products program and the January 2025 draft guidance on AI to support regulatory decisions. We help customers use AI on top of Dotmatics data for structure-activity relationship triage, assay QC anomaly detection, ELN search and summarization, and automated Prism figure generation. Our pattern connects AI agents to Luma, LabArchives, and Geneious through the Model Context Protocol with read-mostly, audited access — see our Dotmatics AI Integration page.
Yes. GraphPad Prism is ubiquitous in pharma analytical labs for dose-response, survival, and statistical analysis, but most organizations run it as desktop software with limited governance. We help customers move to GraphPad Prism organization licenses, standardize template libraries, automate data pipelines from ELN and LIMS into Prism-ready tables, and apply validation controls so Prism-generated figures can be used in GLP and regulatory contexts. This typically replaces ad-hoc Excel preprocessing, which is the single biggest source of data integrity findings in bioanalytical labs.
Yes. SnapGene and Geneious Prime/Biologics are widely adopted in molecular biology and biologics teams but are often isolated from the rest of the R&D stack. We build pipelines that synchronize sequence records, annotation data, and biologics registration between Geneious, Benchling, Dotmatics Luma, and Veeva Vault RIM. We use Geneious REST APIs for automation, and we wrap SnapGene file generation into CI-style pipelines for cloning workflows so constructs are reproducible and traceable across teams and sites.
LabArchives is the most widely deployed ELN in academic research and is also used by translational science groups inside pharma. It is part of the Dotmatics family and integrates with the rest of the Luma ecosystem. We help enterprises roll out LabArchives across translational and discovery biology teams, enforce templated entries for reproducibility, connect it to Veeva Vault and SharePoint for document handoff, and apply the ISPE GAMP Good Practice Guide on Records and Data Integrity to govern ELN use across GxP and non-GxP contexts.
Chemistry migration is usually the highest-risk part of any Dotmatics program because compound identity must be preserved exactly across systems. We follow an established pattern: extract raw SD files and registry exports, normalize structures with canonical tautomer and stereochemistry handling, reconcile salt and parent relationships, and reload into Dotmatics registration with deterministic ID mapping. We validate against documented rules from the RSC and IUPAC where applicable, and we keep a full bidirectional audit mapping so scientists can always reconcile a Luma compound ID back to its legacy registry number.
Most engagements start with a two to four week discovery sprint. We interview key scientists, IT owners, QA, and validation leads, review your current Dotmatics or legacy footprint, and deliver a prioritized roadmap with cost ranges, validation scope, and integration architecture. From there we move into implementation phases — typically configuration, integration, validation, cutover, and hypercare. Book a working session via our book a meeting page or explore the integrations index for the other platforms we connect to Dotmatics.
Ready to Accelerate Your Dotmatics Program?
From Luma migration to AI agents on R&D data and full GxP validation, we help pharma and biotech teams get more from their Dotmatics investment. Let us show you a roadmap tailored to your stack.
Book a Meeting