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TriNetX EVIDEX

by TriNetXtrinetx.com
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OVERVIEW

A cloud-based pharmacovigilance platform for integrated signal detection, management, and analytics using global real-world data.

TriNetX EVIDEX is a cloud-based, software-as-a-service (SaaS) platform purpose-built for pharmacovigilance (PV) teams in life science organizations. It provides a unified, panoramic view of drug safety data by combining the TriNetX global network of de-identified Real-World Data (RWD)—over 250 million patient records—with public safety data sources like FAERS, VigiBase, EVDAS, ICSR, Health Canada, ClinicalTrials.gov, and VAERS.

EVIDEX is designed to replace legacy systems, offering an intuitive user interface that eliminates the need for users to be data scientists to gain insights. The platform streamlines workflows, ensures audit readiness, and helps maintain regulatory compliance, including being fully validated off-the-shelf based on GVP Module IX–Signal Management guidelines. Key capabilities span the entire signal management lifecycle: detection, assessment, validation, prioritization, and reporting.

Key Features & Capabilities:

  • Multi-Source Signal Detection: Run multi-modal signal detection from harmonized RWD and public safety databases in a single system.
  • Automated Workflows: Find and validate new potential signals within RWD and set automated review workflows.
  • Advanced Analytics: Use multi-source comparisons, trend analysis, and disproportionality calculations (ROR, PRR, EGBM) in seconds.
  • Signal Management: Track and resolve safety signals from any data source with audit-ready tools, customizable filters, and detailed user-level tracking.
  • Real-World Data Integration: Immediate access to over 250 million de-identified global patient records for signal refinement and characterization.
  • GVP Module IX Compliance: Off-the-shelf validation and audit trail creation to fulfill regulatory duties.

The platform is flexible and scalable, serving organizations with both high and low volumes of signals, and is supported by a dedicated Product Specialist Team offering ongoing training and Hypercare Support during implementation.

RATING & STATS

Customers
100+
Founded
2013

KEY FEATURES

  • Multi-Source Signal Detection (RWD, FAERS, VigiBase, ICSR)
  • Access to 250M+ Global De-identified Patient Records
  • Automated Signal Detection and Review Workflows
  • Disproportionality Calculation (ROR, PRR, EGBM)
  • GVP Module IX Compliant Signal Management
  • Real-Time Dashboarding and Data Visualizations
  • Customizable Signal Algorithms and Prioritization

PRICING

Model: enterprise
Pricing is not publicly disclosed and is typically negotiated based on the client's use case, scope of work, and data access requirements.

TECHNICAL DETAILS

Deployment: saas, cloud
Platforms: web
🔌 API Available

USE CASES

Integrated Signal Detection and ManagementPharmacovigilance (PV) and Drug SafetyRisk Minimization Study EvaluationPost-Marketing Safety SurveillanceReal-World Evidence (RWE) Generation

INTEGRATIONS

Internal ICSR DatabasesFAERSVigiBaseEVDASHealth CanadaClinicalTrials.govVAERS

COMPLIANCE & SECURITY

Compliance:
HIPAAGDPRLGPDGVP Module IXISO 27001:2022
Security Features:
  • 🔒De-identified Real-World Data (RWD)
  • 🔒REST API with Best-in-Class Authentication
  • 🔒Data Encryption (at rest and in transit)
  • 🔒Audit Trail Creation
  • 🔒AWS Identity and Access Management (IAM) Controls

SUPPORT & IMPLEMENTATION

Support: dedicated specialist, on-demand support, on-site support, web meetings
Implementation Time: 1-3 months
Target Company Size: medium, enterprise
TRAINING AVAILABLE

PROS & CONS

✓ Pros:
  • +Unmatched, panoramic view of global, real-world data (250M+ patient records).
  • +Unified system for multi-source signal detection and management.
  • +Intuitive user interface designed for pharmacovigilance teams, not just data scientists.
  • +Fast validated implementation and audit readiness for regulatory compliance.
  • +High value for the cost compared to legacy systems.
✗ Cons:
  • -Pricing is not publicly disclosed (enterprise model).
  • -Limited public reviews and third-party ratings available.
  • -Focus is highly specialized (pharmacovigilance), limiting broader use.

ABOUT TRINETX

Other software by TriNetX:
TriNetX (Oncology Analytics & Quality ReportingReal-world evidence (RWE) oncology)