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Oracle Argus Safety

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OVERVIEW

Market-leading pharmacovigilance solution for automated adverse event case processing, global regulatory reporting, and safety signal management.

Oracle Argus Safety is a comprehensive, industry-proven pharmacovigilance platform designed for life sciences companies, including pharmaceutical manufacturers, sponsors, and Contract Research Organizations (CROs). It is widely considered the gold standard for drug safety management, supporting both pre-market (clinical trials) and post-market surveillance for drugs, biologics, vaccines, devices, and combination products.

Key Benefits and Capabilities:

  • Workflow Automation: Features for intake, case prioritization, field validations, coding, narrative generation, and regulatory submission can reduce manual work by 50% or more, maximizing case processing efficiency.
  • Global Regulatory Compliance: The system is continuously updated to ensure compliance with a wide range of global regulations and standards, including ICH E2B (R3), E2B (R2), PMDA, FDA (eVAERS, eMDR), and IDMP.
  • End-to-End Case Management: It provides a central, secure platform for documenting all adverse event data, including source documents, follow-up information, medical coding (MedDRA, WHO Drug), medical assessments, and regulatory reports.
  • Safety Analytics: Argus Advanced Cloud includes Oracle Analytics, an AI-powered solution that provides deep insights into safety data, workflow metrics, and submission compliance to facilitate faster, informed decision-making and proactive risk management.
  • Scalability: The platform is highly scalable, designed to handle millions of safety cases annually and support the needs of companies ranging from small organizations to large global enterprises.

Target Users & Use Cases:

  • Drug Safety/Pharmacovigilance teams
  • Regulatory Affairs professionals
  • Medical Reviewers
  • Quality Assurance teams
  • CROs managing safety data for clients

The primary use case is to streamline and automate the entire drug safety lifecycle, ensuring timely and accurate regulatory adherence while enabling proactive signal detection.

RATING & STATS

User Rating
4.0/5.0
10 reviews
Customers
1,000+
Founded
1997

KEY FEATURES

  • Adverse Event Case Processing and Management
  • Global Regulatory Reporting (ICH E2B, PMDA, FDA)
  • Workflow Automation and Conditional Touchless Processing
  • Safety Signal Detection and Risk Management
  • Medical Coding (MedDRA, WHO Drug)
  • Safety Analytics and Business Intelligence Dashboards
  • Clinical-to-Safety Reconciliation
  • Document Management Integration

PRICING

Model: enterprise
Enterprise-level subscription pricing is not publicly disclosed and requires direct consultation with Oracle Sales. It is typically licensed based on usage, modules, and number of users.

TECHNICAL DETAILS

Deployment: cloud, on_premise, saas
Platforms: web
🔌 API Available

USE CASES

Adverse Event Management (AEM)Global Regulatory Compliance and SubmissionPre-market and Post-market Safety SurveillanceDrug, Biologic, Vaccine, and Device Safety Management

INTEGRATIONS

Oracle Argus InsightOracle Empirica Signal (Signal Detection)Clinical Trial Solutions (e.g., Oracle Clinical)Safety Case Intake SystemsDocument Management Systems (e.g., Documentum)Single Sign-On (SSO) Providers (e.g., PingFederate)

COMPLIANCE & SECURITY

Compliance:
ICH E2B (R3)FDA 21 CFR Part 11EU Annex 11GDPR (Data Privacy Methodologies)PMDA StandardsIDMP
Security Features:
  • 🔒Single Sign-On (SSO)
  • 🔒Two-Factor Authentication (via SSO integration)
  • 🔒HTTPS/SSL Encryption
  • 🔒Configurable Password Complexity
  • 🔒Data Privacy Methodologies (PII Protection)

SUPPORT & IMPLEMENTATION

Support: email, phone, 24/7 support, online knowledge base
Implementation Time: 1-3 months
Target Company Size: medium, enterprise
TRAINING AVAILABLE

PROS & CONS

✓ Pros:
  • +Market-leading solution and industry standard for pharmacovigilance
  • +Robust automation features significantly reduce manual case processing time
  • +Comprehensive, built-in support for global regulatory compliance (E2B, FDA, EMA, PMDA)
  • +Highly scalable to handle millions of cases for global enterprises and CROs
  • +Integrated safety analytics for proactive signal detection and compliance monitoring
✗ Cons:
  • -High total cost of ownership (TCO) typical of enterprise Oracle products
  • -Complexity and steep learning curve for new users and administrators
  • -Implementation and configuration can be lengthy and require specialized consultants
  • -Limited public user reviews and transparency on pricing

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