Natera, Inc.
↗Austin, Texas, United States
Natera is a leading diagnostics company headquartered in Austin, Texas that specializes in cell-free DNA (cfDNA) testing across oncology, women's health, and organ transplant sectors. Founded in 2004 by Matthew Rabinowitz and Jonathan Sheena, the company has pioneered molecular residual disease (MRD) detection and non-invasive prenatal testing (NIPT). Natera's proprietary technology combines novel molecular biology with bioinformatics software capable of detecting single molecules in blood samples. The company operates as a CLIA-certified laboratory and has expanded significantly through acquisitions including Foresight Diagnostics ($450M, 2025) and Invitae's reproductive health assets (2024).
CLASSIFICATION
Company Type:Diagnostics
Therapeutic Areas:
Industry:Biotechnology / Diagnostics
Sub-Industry:Cell-Free DNA Testing, Molecular Diagnostics, Genetic Testing
SIZE & FINANCIALS
Employees:5001-10000
Revenue:$2.3B
Founded:2004
Ownership:public
Status:operating
FUNDING
Stage:Public
Total Raised:$152M
STOCK
Exchange:NASDAQ
Ticker:NTRA
Market Cap:$34.7B
PIPELINE
Stage:Commercial + PMA Pending
Lead Drug Stage:Signatera CDx PMA submitted for MIBC (Feb 2026)
Modalities:Cell-free DNA (cfDNA), Circulating Tumor DNA (ctDNA), Non-invasive prenatal testing (NIPT), Molecular residual disease (MRD) detection
Active Trials:4
Trial Phases:Phase 2: 1 | Phase 3: 3
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Subsidiaries:Foresight Diagnostics (acquired 2025)
Key Partnerships:Roche/Genentech (Signatera for Tecentriq/atezolizumab), Exelixis (Phase 3 colorectal cancer trial), NVIDIA (AI foundation models collaboration), BGI Genomics, Foundation Medicine
COMPETITION
Position:Leader
Competitors:Guardant Health (Guardant360, Reveal), Invitae, Foundation Medicine (FoundationOne Liquid CDx), Exact Sciences (Oncotype, Cologuard), Myriad Genetics, CareDx, Illumina (GRAIL), LabCorp +1 more
LEADERSHIP
Key Executives:
Matthew Rabinowitz - Co-Founder, Executive Chairman
Steve Chapman - Chief Executive Officer
Robert Schueren - Chief Operating Officer
Michael Brophy - Chief Financial Officer
Scientific Founders:Matthew Rabinowitz (PhD, Stanford), Jonathan Sheena
Board Members:Matthew Rabinowitz (Executive Chairman), Steve Chapman (CEO), Dr. Monica Bertagnolli (joined March 2025; former NIH Director), Dr. Marcus (member since 2017)
LINKS
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