Sionna Therapeutics
↗Waltham, Massachusetts, USA
Sionna Therapeutics is a clinical-stage biopharmaceutical company focused on transforming the treatment of cystic fibrosis (CF). The company is developing a pipeline of novel small molecules designed to normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein by directly stabilizing its first nucleotide-binding domain (NBD1), a target historically considered undruggable.
Founded in 2019 and headquartered in Waltham, Massachusetts, Sionna aims to deliver differentiated therapies that provide superior efficacy compared to the current standard of care. The company's pipeline includes multiple NBD1 stabilizers and complementary modulators, with several candidates advancing through clinical trials.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:-
Industry:Biotechnology
Sub-Industry:Cystic Fibrosis Therapeutics
SIZE & FINANCIALS
Employees:51-200
Revenue:$5M-$10M
Founded:2019
Ownership:public
Status:operating
FUNDING
Stage:Post-IPO
Total Raised:$332M
Investors:Enavate Sciences, Viking Global Investors, Perceptive Advisors, OrbiMed, RA Capital, TPG's The Rise Fund, Atlas Venture, Cystic Fibrosis Foundation, T. Rowe Price, Q Healthcare Holdings
STOCK
Exchange:NASDAQ
Ticker:SION
Market Cap:$1.63B
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 2a
Modalities:Small molecule
Active Trials:4
Trial Phases:Phase 1: 2 | Phase 2: 2
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:AbbVie: Licensed multiple clinical-stage CF compounds (galicaftor, navocaftor, ABBV-2851) in July 2024.
COMPETITION
Position:Emerging
Competitors:Vertex Pharmaceuticals, Stablix
LEADERSHIP
Key Executives:
Mike Cloonan - President and Chief Executive Officer
Board Members:Edd Fleming
LINKS
Website:sionnatx.com
LinkedIn:LinkedIn Profile
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