Sentinel Oncology
↗Cambridge, United Kingdom
Sentinel Oncology is a Cambridge-based drug discovery company founded in 2005 that specializes in developing small molecule therapeutics for cancer and other diseases with unmet medical needs. The company is particularly focused on creating innovative treatments for primary brain tumors and systemic cancers that metastasize to the brain. With a core team of 9 employees, Sentinel leverages deep medicinal chemistry expertise to design highly selective and targeted oncology candidates. The company operates on a partnership-driven business model, licensing its drug candidates to pharmaceutical partners for further development and commercialization while maintaining research operations in Cambridge, UK.
CLASSIFICATION
SIZE & FINANCIALS
Employees:1-50
Founded:2005
Ownership:private
Status:operating
FUNDING
Stage:Grant-funded
Total Raised:$2.73M
Investors:Innovate UK, Biomedical Catalyst, Medeor Pharma, Cambridge Enterprise Ventures, O2h Ventures, Wellcome Trust
PIPELINE
Stage:Preclinical to Phase 1
Lead Drug Stage:Phase 1 (SOL578)
Modalities:Small molecule, Chk1 inhibitor, PLK1 inhibitor
Active Trials:1
Trial Phases:Phase 1: 2
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:PharmaEngine Inc., Otsuka Pharmaceutical (McQuade Center for Strategic Research and Development), PhoreMost Limited, Oncothyreon Inc.
COMPETITION
Position:Niche Player
Competitors:Echelon Biosciences, Forma Therapeutics, Terpenoid Therapeutics, BrightPath Biotherapeutics, Astex Pharmaceuticals, Jazz Pharmaceuticals, Moderna, BeiGene
LEADERSHIP
Key Executives:
Robert G. Boyle - Founder, Chief Executive Officer & Chair
Stuart Travers - Chief Operating Officer
David Walker - Director of Chemistry
Kyla Grimshaw - Director of Biology
Scientific Founders:Robert G. Boyle, Stuart Travers, Gavin Simpson
Board Members:Dan Cowell (Non Executive Director)
LINKS
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