Senti Biosciences
↗South San Francisco, California, USA
Senti Biosciences is a clinical-stage biotechnology company developing next-generation cell and gene therapies engineered with proprietary gene circuit platform technologies. Founded in 2016 by pioneers in synthetic biology, the company uses logic-gated genetic circuits to create smarter therapeutics for patients with incurable diseases. The company specializes in off-the-shelf allogeneic CAR-NK (chimeric antigen receptor natural killer) cell therapies that combine selective targeting with safety features to minimize off-target toxicity. Senti Bio went public via SPAC merger in June 2022 and is developing a pipeline of product candidates across oncology indications.
CLASSIFICATION
SIZE & FINANCIALS
Employees:51-200
Revenue:Pre-commercial
Founded:2016
Ownership:public
Status:operating
FUNDING
Stage:Post-IPO
Total Raised:$158M
Investors:New Enterprise Associates (NEA), Celadon Partners, Leaps by Bayer, Nantahala Capital, The Red Hook Fund LP
STOCK
Exchange:NASDAQ
Ticker:SNTI
Market Cap:$44.3M
PIPELINE
Stage:Phase 1
Lead Drug Stage:Phase 1
Modalities:CAR-NK cells, Gene circuit engineering, Off-the-shelf cell therapy
Active Trials:1
Trial Phases:Phase 1: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Celest Therapeutics (Shanghai), California Institute for Regenerative Medicine (CIRM), GeneFab (Celadon Partners-backed CDMO)
COMPETITION
Position:Emerging
Competitors:Fate Therapeutics, Nkarta Therapeutics, Artiva Biotherapeutics, Calidi Biotherapeutics, Tmunity Therapeutics
LEADERSHIP
Key Executives:
Dr. Tim Lu - Chief Executive Officer, Co-founder
Dr. Kanya Rajangam - Chief Medical Officer, Head of Research & Development
Yvonne Li - Interim Chief Financial Officer, Treasurer
Michael Rhee - General Counsel, Secretary
Karin Thacker - Vice President, Head of Regulatory and Quality
Scientific Founders:Dr. Tim Lu, Dr. Jim Collins, Dr. Phillip Lee, Dr. Wilson Wong
Board Members:Dr. Tim Lu (CEO, Board Member), Fran Schulz (Board Member, Audit Committee Chair), Feng Hsiung (Board Member), Bryan Baum (Board Member), NEA Representative (Mathers) (Board Member), Dr. Jim Collins (Board Member (Founder))
LINKS
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