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Prime Medicine, Inc.
↗Cambridge, Massachusetts, USA
Prime Medicine is a biotechnology company focused on developing a new class of differentiated, one-time curative genetic therapies using its proprietary 'Prime Editing' platform. Prime Editing acts as a 'DNA word processor,' allowing for precise 'search and replace' genetic edits without causing double-strand DNA breaks, potentially addressing approximately 90% of known disease-causing mutations.
The company is currently focused on a diversified portfolio of programs targeting liver, lung, and immunology/oncology indications. Its lead programs include PM577 for Wilson's Disease and PM647 for Alpha-1 Antitrypsin Deficiency (AATD), with clinical data anticipated in 2027.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Gene Editing / Genetic Medicines
SIZE & FINANCIALS
Employees:201-500
Revenue:$1M-$10M
Founded:2019
Ownership:public
Status:operating
FUNDING
Stage:Post-IPO
Total Raised:$315M (Initial Series A/B)
Investors:GV, Arch Venture Partners
STOCK
Exchange:NASDAQ
Ticker:PRME
Market Cap:$0.63B
PIPELINE
Stage:Phase 1/2
Lead Drug Stage:Phase 1/2
Modalities:Gene therapy, Prime Editing
Active Trials:1
Trial Phases:Phase 1: 1 | Phase 2: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Bristol Myers Squibb (ex vivo T-cell Prime Editor products), Cystic Fibrosis Foundation (Cystic Fibrosis development), Cimeio Therapeutics (Shielded-Cell & Immunotherapy Pairs)
COMPETITION
Position:Emerging
Competitors:Beam Therapeutics, Editas Medicine, Intellia Therapeutics, CRISPR Therapeutics
LEADERSHIP
Key Executives:
Allan Reine - CEO
Svetlana Makhni - CFO
Ann Lee - CTO
Scientific Founders:David R. Liu, Andrew Anzalone
Board Members:Jeffrey Marrazzo, Allan Reine, Thomas Cahill, Wendy Chung, Kaye Foster, Michael Kelly, Robert Nelsen, David Schenkein
LINKS
Website:primemedicine.com
LinkedIn:LinkedIn Profile
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