Okklo Life Sciences
↗Nijmegen, Netherlands
Okklo Life Sciences is a biopharmaceutical company specializing in the development of therapeutic cyclodextrins using its proprietary OCTOPlex technology platform. The company utilizes 'host-guest' chemistry to design modified cyclodextrins that can selectively capture and neutralize target molecules, such as toxins, metabolites, or drugs, within the body.
Okklo focuses on orphan and neglected diseases, with active programs in hematology (anticoagulant reversal), lysosomal storage diseases (Niemann-Pick Type C, ASMD), and cystic fibrosis. The company frequently operates through strategic spin-offs and joint ventures, most notably Alveron Pharma, which was established to advance its lead hematology assets into clinical development.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Therapeutic Cyclodextrins / Rare Disease
SIZE & FINANCIALS
Employees:1-50
Revenue:Pre-revenue
Founded:2011
Ownership:private
Status:operating
FUNDING
Stage:Seed
Total Raised:$15M+
Investors:Thuja Capital, Waterman Ventures, Oost NL, RedMedTech Discovery Fund, Sanquinnovate, Rijksdienst voor Ondernemend Nederland (RVO)
PIPELINE
Stage:Phase 1
Lead Drug Stage:Phase 1 (OKL-1111)
Modalities:Small molecule, Modified Cyclodextrins
Active Trials:1
Trial Phases:Phase 1: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Subsidiaries:Alveron Pharma (Joint Venture/Spin-off)
Key Partnerships:Sanquin Blood Supply Foundation (R&D and Commercialization), SolAeroMed (Cystic Fibrosis collaboration), ProductLife Group (Regulatory support via acquisition of Zwiers Consultancy)
COMPETITION
Position:Niche Player
Competitors:Azafaros, Avrobio, Gain Therapeutics, Cyclo Therapeutics, IntraBio
LEADERSHIP
Key Executives:
Alex Zwiers - COO
Stephan Peters - CSO
Scientific Founders:Alex Zwiers, Stephan Peters
Board Members:Joost Meijers (Scientific Advisory Board Chair)
LINKS
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