NextCure, Inc.
↗Beltsville, Maryland, USA
NextCure is a clinical-stage biopharmaceutical company focused on discovering and developing novel, first-in-class immunomedicines to treat cancer and other immune-related diseases. The company utilizes its proprietary FIND-IO™ platform to identify novel cell surface molecular targets and biological pathways that mediate immune responses, aiming to restore normal immune function in patients who do not respond to current therapies.
The company's strategy emphasizes the development of differentiated mechanisms of action, including Antibody-Drug Conjugates (ADCs) and fusion proteins. NextCure is currently advancing a pipeline of clinical candidates targeting various solid tumors and hematologic malignancies, often in combination with established checkpoint inhibitors like pembrolizumab.
CLASSIFICATION
SIZE & FINANCIALS
Employees:1-50
Revenue:$0M (Clinical-stage)
Founded:2015
Ownership:public
Status:operating
FUNDING
Stage:Post-IPO
Total Raised:$21.5M (Recent Private Placement)
Investors:Ikarian Capital, Squadron Capital Management, Affinity Healthcare Fund, Exome Asset Management
STOCK
Exchange:NASDAQ
Ticker:NXTC
Market Cap:$45.3M
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 1b/2
Modalities:mAb, ADC, Fusion protein
Active Trials:5
Trial Phases:Phase 1: 4 | Phase 2: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Simcere Zaiming (SIM0505 development and commercialization), LegoChem Biosciences (ADC technology collaboration), Yale University (Research collaboration with Dr. Lieping Chen)
COMPETITION
Position:Emerging
Competitors:MacroGenics, Xilio Therapeutics, Galecto, Incyte
LEADERSHIP
Key Executives:
Michael Richman - President & CEO
Timothy Mayer - COO
Udayan Guha - CMO
Scientific Founders:Lieping Chen, M.D., Ph.D.
Board Members:David Kabakoff (Chairman), Elaine V. Jones, John G. Houston, Ellen G. Feigal
LINKS
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