IPS Biopharma AG
↗Bern, Switzerland
IPS Biopharma AG is the European subsidiary of Immunophotonics, Inc., a clinical-stage biotechnology company pioneering the field of Interventional Immuno-Oncology. The company focuses on transforming standard-of-care tumor ablation procedures into a systemic immunotherapy. Its proprietary technology, known as inCVAX, involves the intratumoral injection of an immune-activating drug immediately following a local tumor destruction technique like thermal ablation.
The company's lead asset, IP-001, is a proprietary glycan polymer (galactated chitosan) designed to act as both an antigen depot and a potent immune stimulant. By sequestering tumor antigens liberated during ablation and recruiting antigen-presenting cells, IP-001 induces a systemic, tumor-specific T-cell response. This approach aims to eliminate not only the primary treated tumor but also distant micrometastases, addressing the high unmet need for preventing cancer recurrence and treating metastatic disease.
CLASSIFICATION
SIZE & FINANCIALS
Employees:1-50
Revenue:$0M-$1M
Founded:2013
Ownership:private
Status:operating
FUNDING
Stage:Series B
Total Raised:$93.9M
Investors:Zubizoom, iSelect Fund, BioGenerator, Cultivation Capital, Johnson & Johnson Innovation, European Union (Grants), Horizen Capital, ROVAQ Ventures, SeedFolio
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 2
Modalities:Small molecule, Carbohydrate polymer, Immunoadjuvant
Active Trials:3
Trial Phases:Phase 1: 1 | Phase 2: 2
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Parent Company:Immunophotonics, Inc.
Key Partnerships:AngioDynamics (Co-development of IP-001 with ablation devices), Johnson & Johnson Innovation (Strategic collaboration), Swiss Group for Clinical Cancer Research (SAKK) (Clinical trial partner), Cancer Center Amsterdam (Clinical collaboration), CIRSE (Collaboration for INJECTABL-3 pivotal trial)
COMPETITION
Position:Niche Player
Competitors:Boston Scientific (BTG), Medtronic, Agenus, Turnstone Biologics, Achilles Therapeutics
LEADERSHIP
Key Executives:
Miguel Zubizarreta - CEO
Robert Arch - President
Tomas Hode - Co-founder & Chief Innovation Officer
Lu Alleruzzo - Co-founder & Director
Scientific Founders:Tomas Hode, Lu Alleruzzo, Robert Nordquist
Board Members:Bobby Sandage (Chairman), Jonathan Knowles, Miguel Zubizarreta, Lu Alleruzzo
LINKS
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