Intellia Therapeutics
↗Cambridge, USA
Intellia Therapeutics is a leading clinical-stage genome editing company focused on developing curative therapeutics using CRISPR/Cas9 technology. The company specializes in both in vivo programs, where CRISPR is delivered systemically to edit genes inside the human body, and ex vivo programs, where cells are edited outside the body for immuno-oncology and autoimmune diseases.
Headquartered in Cambridge, Massachusetts, Intellia was co-founded by Nobel laureate Jennifer Doudna and has established itself as a pioneer in the gene-editing field. The company is currently advancing several late-stage clinical candidates aimed at treating rare genetic diseases such as ATTR amyloidosis and hereditary angioedema (HAE).
CLASSIFICATION
SIZE & FINANCIALS
Employees:201-500
Revenue:$50M-$100M
Founded:2014
Ownership:public
Status:operating
FUNDING
Stage:Public
Total Raised:$85M (Pre-IPO)
Investors:Atlas Venture, OrbiMed, Fidelity Management and Research Company, Regeneron Pharmaceuticals, Novartis
STOCK
Exchange:NASDAQ
Ticker:NTLA
Market Cap:$1.61B
PIPELINE
Stage:Phase 3
Lead Drug Stage:Phase 3
Modalities:CRISPR/Cas9, LNP (Lipid Nanoparticle) Delivery, Gene Knockout, Gene Insertion
Active Trials:5
Trial Phases:Phase 1: 2 | Phase 2: 1 | Phase 3: 2
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Regeneron (Co-development of nex-z and Hemophilia B program), Novartis (Collaboration on ex vivo stem cell programs)
COMPETITION
Position:Leader
Competitors:CRISPR Therapeutics, Beam Therapeutics, Editas Medicine, Caribou Biosciences, Alnylam Pharmaceuticals
LEADERSHIP
Key Executives:
John Leonard, M.D. - President and CEO
Birgit Schultes, Ph.D. - Executive VP and CSO
David Lebwohl, M.D. - Chief Medical Officer
Scientific Founders:Jennifer Doudna, Erik Sontheimer, Luciano Marraffini, Rodolphe Barrangou
Board Members:Frank Verwiel (Chairman), Brian Goff, Muna Bhanji, Fred Cohen
LINKS
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