Company Directory > Biotech > Immune System Key Ltd. (ISK)
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Immune System Key (ISK) Ltd. is a privately held, clinical-stage biotechnology company focused on the discovery and development of innovative treatments for malignant and autoimmune diseases. The company's therapeutic assets are based on novel human secreted peptides discovered by its founders. ISK's flagship candidate, Nerofe (dTCApFs), is a peptide derivative designed to act through a novel mechanism involving the T1/ST2 receptor. The company is exploring Nerofe's potential in various oncology indications, including Acute Myeloid Leukemia (AML), pancreatic cancer, and metastatic colorectal cancer, often in combination with other agents to modulate the tumor microenvironment.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Oncology biotech
SIZE & FINANCIALS
Employees:1-50
Founded:2005
Ownership:private
Status:operating
FUNDING
Stage:Grant-funded
Total Raised:$2.5M (approx. in grants)
Investors:Israel Innovation Authority
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 2a
Modalities:Peptide
Active Trials:2
Trial Phases:Phase 1: 1 | Phase 2: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Georgetown University (Clinical trials), Johnson & Johnson Innovation – JLABS (Resident company)
COMPETITION
Position:Emerging
Competitors:Jazz Pharmaceuticals, Sana Biotechnology, Kite Pharma
LEADERSHIP
Key Executives:
Yoram Devary - Co-Founder & CTO
Uziel Sandler - Co-Founder
Scientific Founders:Uziel Sandler, Yoram Devary
LINKS
Website:immunesk.com
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