Hone Bio
↗Bristol, United Kingdom
Hone Bio (formerly CytoSeek Ltd) is a discovery-stage biotechnology company spun out of the University of Bristol in 2017. Originally founded to develop next-generation cell therapies using artificial membrane-binding protein (AMBP) technology, the company has evolved to focus on lipid nanoparticle drug delivery through its NanoPilot targeting technology. The company's core innovation involves creating engineered proteins that spontaneously insert into cell membranes without genetic modification, adding new functionalities to therapeutic cells. Early applications targeted solid tumors in cancer, heart disease, osteoarthritis, and diabetic wound healing.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Cell Therapy, Drug Delivery
SIZE & FINANCIALS
Employees:1-50
Founded:2017
Ownership:private
Status:operating
FUNDING
Stage:Series A
Total Raised:$7.34M
Investors:Science Creates Ventures, Parkwalk Advisors, Bristol Private Equity Club, Venture Capital Fund UKI2S, University of Bristol Enterprise Fund, Future Planet Capital, KCP Nominees, Luminous Ventures, Meltwind Advisory, Outsized Ventures, SCVC
PIPELINE
Stage:Preclinical
Lead Drug Stage:Proof of Concept
Modalities:Cell therapy, Lipid Nanoparticles (LNPs), Protein engineering, CAR-T enhancement
Active Trials:0
Trial Phases:-
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:University of Bristol (spin-out; ongoing research collaboration)
COMPETITION
Position:Emerging
Competitors:Gilead Sciences (CAR-T leader), Bristol Myers Squibb (CAR-T/cell therapy), Novartis (CAR-T leader), Janssen (cell therapy), Allogene Therapeutics, Cellectis, Atara Biotherapeutics, CARsgen Therapeutics +2 more
LEADERSHIP
Key Executives:
Dr. Carolyn Porter - CEO
Clive Stanway - Non-Executive Director
Scientific Founders:Professor Adam Perriman (Founder / Scientific Advisor)
Board Members:Dr. Carolyn Porter (CEO & Director), Clive Stanway (Non-Executive Director)
LINKS
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