Enlivex Therapeutics Ltd.
↗Ness Ziona, Israel
Enlivex Therapeutics is a clinical-stage immunotherapy company developing a novel class of macrophage reprogramming therapies. Its proprietary platform, Allocetra™, is an allogeneic, off-the-shelf cell therapy designed to reprogram macrophages into their homeostatic state, effectively rebalancing a life-threatening or chronic unbalanced immune system without suppressing it.
The company's primary focus is on treating conditions characterized by immune system hyper-responses, such as sepsis and solid tumors, as well as chronic inflammatory conditions like osteoarthritis. By engaging macrophages and dendritic cells, Allocetra™ aims to avert cytokine storms and restore immune balance. Enlivex is currently advancing multiple clinical programs, with significant recent milestones in knee osteoarthritis and sepsis.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Macrophage reprogramming immunotherapy
SIZE & FINANCIALS
Employees:1-50
Revenue:$0M (Clinical-stage)
Founded:2005
Ownership:public
Status:operating
FUNDING
Stage:Post-IPO
Total Raised:$286.9M
Investors:Citizens Financial Group, Morgan Stanley, Renaissance Technologies, Citadel Advisors, Susquehanna International Group
STOCK
Exchange:NASDAQ
Ticker:ENLV
Market Cap:$233M
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 2
Modalities:Cell therapy, Allogeneic therapy
Active Trials:3
Trial Phases:Phase 1: 1 | Phase 2: 2
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Subsidiaries:Bio Blast Pharma (merged)
Key Partnerships:Hadassah Medical Center (Scientific collaboration), Charité Berlin (Clinical research collaboration)
COMPETITION
Position:Emerging
Competitors:Agenus, Inovio Pharmaceuticals, Sorrento Therapeutics, Pyxis Oncology, Tevogen Bio
LEADERSHIP
Key Executives:
Oren Hershkovitz - CEO
Shai Novik - Executive Chairman
Shachar Shlosberger - CFO
Scientific Founders:Prof. Dror Mevorach
Board Members:Shai Novik, Roger Pomerantz, Matteo Renzi, Abraham Havron, Gili Hart, Andrew Singer
LINKS
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