Drugs for Neglected Diseases initiative (DNDi)
↗Geneva, Switzerland
DNDi is a non-profit medical research and development organization that focuses on developing new treatments for neglected diseases, such as leishmaniasis, Chagas disease, sleeping sickness, and pediatric HIV. Founded in 2003 by Médecins Sans Frontières (MSF) and other public partners, it operates on a collaborative, needs-driven model, acting as a 'conductor of a virtual orchestra' by partnering with academia, the pharmaceutical industry, and governments.
The organization bridges R&D gaps by initiating and coordinating drug development projects from discovery through to clinical trials and regulatory approval. DNDi is known for its 'public interest R&D' model, which prioritizes patient needs over profit, ensuring that new medical innovations are affordable, available, and adapted to the communities that need them most.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Non-profit R&D / Infectious Diseases
SIZE & FINANCIALS
Employees:201-500
Revenue:$50M-$100M
Founded:2003
Ownership:nonprofit
Status:operating
FUNDING
Stage:Non-profit / Grant-funded
Total Raised:$1000M+
Investors:Bill & Melinda Gates Foundation, Wellcome Trust, UK International Development (FCDO), Médecins Sans Frontières (MSF), Unitaid, GHIT Fund
PIPELINE
Stage:Commercial
Lead Drug Stage:Approved (Fexinidazole)
Modalities:Small molecule, Repurposed drugs, Fixed-dose combinations
Active Trials:16
Trial Phases:Phase 1: 4 | Phase 2: 6 | Phase 3: 4 | Phase 4: 2
FDA Approvals:1
EMA Approvals:1
CORPORATE STRUCTURE
Subsidiaries:DNDi North America, DNDi Latin America, DNDi Africa, DNDi South Asia, DNDi Japan
Key Partnerships:Sanofi (Sleeping Sickness), Eisai (Chagas Disease), Takeda (Visceral Leishmaniasis), Dubai Health (Neglected Diseases research), WHO (Global health policy and guidelines)
COMPETITION
Position:Leader
Competitors:PATH, Medicines for Malaria Venture (MMV), Global Alliance for TB Drug Development, Sabin Vaccine Institute
LEADERSHIP
Key Executives:
Luis Pizarro - Executive Director
Laurent Fraisse - Director of R&D
Scientific Founders:Bernard Pécoul, Médecins Sans Frontières (MSF)
Board Members:Marie-Paule Kieny (Chair), Christos Christou, Noor Hisham Abdullah
LINKS
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