Company Directory > Biotech > ClearB Therapeutics, Inc.
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ClearB Therapeutics is a clinical-stage biotechnology company focused on developing therapeutic vaccines to achieve a functional cure for chronic hepatitis B (CHB) infection. The company's approach is grounded in proprietary insights derived from studying rare-event infection resolution in patients who have successfully cleared the virus. Their lead candidate, CLB-4000, is a bivalent subunit therapeutic vaccine consisting of HBsAg variants (CLB-405 and CLB-505) combined with a novel saponin-based adjuvant, TQL-1055, licensed from Adjuvance Technologies. The company is currently evaluating this candidate in Phase 1b clinical trials.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Infectious Diseases
SIZE & FINANCIALS
Employees:1-50
Revenue:$1M-$5M
Founded:2017
Ownership:private
Status:operating
FUNDING
Stage:Venture Capital-Backed
Investors:Morningside Ventures
PIPELINE
Stage:Phase 1
Lead Drug Stage:Phase 1b
Modalities:Therapeutic vaccine, Subunit vaccine, mRNA
Active Trials:3
Trial Phases:Phase 1: 3
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Adjuvance Technologies (License for TQL-1055 adjuvant), Victoria Infectious Diseases Reference Laboratory (Founding collaboration)
COMPETITION
Position:Emerging
Competitors:Ultivue, Ohana Biosciences, Matterworks
LEADERSHIP
Key Executives:
Aileen Rubio - CEO
Aditi Deshpande - Project Lead / Scientist
Wendy Luca - Clinical Development
Scientific Founders:Professor Stephen Locarnini
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