Calico Life Sciences
↗South San Francisco, United States
Calico Life Sciences is an American biotechnology organization founded by Alphabet Inc. and Arthur D. Levinson. The company is dedicated to understanding the basic biology of aging and age-related diseases. By leveraging advanced computing and laboratory technologies, Calico aims to develop first-in-class therapies that enable people to lead longer and healthier lives.
The company operates as a unique hybrid of academic research and biotech industry, focusing on high-risk, long-term scientific questions. Their research spans various model organisms and human genetic data to identify novel targets in oncology, neurodegeneration, and tissue homeostasis. Despite its high-profile backing, Calico maintains a relatively secretive operation, often referred to as 'Alphabet's moonshot for longevity.'
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Longevity and age-related therapeutics
SIZE & FINANCIALS
Employees:201-500
Revenue:$100M-$250M
Founded:2013
Ownership:subsidiary
Status:operating
FUNDING
Stage:Internal Funding
Total Raised:$2.5B
Investors:Alphabet Inc., AbbVie
STOCK
Exchange:NASDAQ
Ticker:GOOGL
Market Cap:$2.15T
PIPELINE
Stage:Phase 2
Lead Drug Stage:Phase 2
Modalities:Small molecule, Monoclonal antibody (mAb), Protein degradation, Cell therapy
Active Trials:8
Trial Phases:Phase 1: 5 | Phase 2: 3
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Parent Company:Alphabet Inc.
Key Partnerships:Mabwell Bioscience (Global licensing for anti-IL-11 antibody 9MW3811), Broad Institute (Collaboration on age-related neurodegeneration and cancer targets), C4 Therapeutics (Targeted protein degradation), UK Biobank (Genetic data collaboration), AncestryDNA (Longevity genetics research)
COMPETITION
Position:Leader
Competitors:Altos Labs, Unity Biotechnology, Life Biosciences, Juvenescence, Elysium Health, Oisin Biotechnologies
LEADERSHIP
Key Executives:
Arthur D. Levinson - CEO
Michael Lenardo - Chief Scientific Officer
Philip R. Kym - Head of Drug Discovery
Scientific Founders:Arthur D. Levinson, Bill Maris, Cynthia Kenyon, David Botstein
Board Members:Shirley M. Tilghman (SAB Chair), Anne Brunet (SAB), Gary Ruvkun (SAB)
LINKS
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