Alkeus Pharmaceuticals
↗Cambridge, USA
Alkeus Pharmaceuticals is a late-stage biopharmaceutical company focused on developing transformative therapies for progressive eye diseases that lead to blindness. The company's primary focus is on Stargardt disease, a leading genetic cause of blindness in children and young adults, and Geographic Atrophy (GA) secondary to dry age-related macular degeneration (AMD).
Their lead candidate, gildeuretinol acetate (ALK-001), is a first-in-class, orally administered, selectively-deuterated form of Vitamin A. It is designed to slow the dimerization of Vitamin A, a process implicated in the accumulation of toxic byproducts in the retina. Alkeus is currently advancing its clinical program toward NDA submission following positive results in its TEASE clinical trials.
CLASSIFICATION
SIZE & FINANCIALS
Employees:51-200
Revenue:Pre-revenue
Founded:2010
Ownership:private
Status:operating
FUNDING
Stage:Series B
Total Raised:$150M
Investors:Bain Capital Life Sciences, TCGX, Wellington Management, Sofinnova Investments
PIPELINE
Stage:Phase 3
Lead Drug Stage:Phase 3 / Pre-NDA
Modalities:Small molecule, Deuterated drug
Active Trials:4
Trial Phases:Phase 2: 1 | Phase 3: 3
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:National Institutes of Health (NIH) - Early research support, Foundation Fighting Blindness
COMPETITION
Position:Leader
Competitors:Belite Bio, Iveric Bio (Astellas), Stargazer Pharmaceuticals, Nanoscope Therapeutics
LEADERSHIP
Key Executives:
Michel Dahan - President and CEO
Joshua Boger, Ph.D. - Executive Chairman
Leonide Saad, Ph.D. - Founder and Director
Carlos Quezada-Ruiz, M.D. - Chief Medical Officer
Scientific Founders:Leonide Saad, Ph.D., Ilyas Washington, Ph.D.
Board Members:Joshua Boger, Leonide Saad, Ricky Sun (Bain Capital)
LINKS
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