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AAVantgarde Bio
↗Milan, Italy
AAVantgarde Bio is a clinical-stage, international biotechnology company headquartered in Italy with operations in London. The company specializes in developing proprietary Adeno-Associated Viral (AAV) vector platforms designed to overcome the DNA cargo capacity limitations of standard AAV vectors, enabling the delivery of large genes for therapeutic purposes.
Founded as a spin-off from the Telethon Institute of Genetics and Medicine (TIGEM) and the University of Naples "Federico II," the company focuses on addressing the root causes of inherited retinal disorders (IRDs). Its lead programs target Usher syndrome type 1B and Stargardt disease, aiming to provide treatments for patients with high unmet medical needs.
CLASSIFICATION
Company Type:Biotech
Therapeutic Areas:
Industry:Biotechnology
Sub-Industry:Gene Therapy / Inherited Retinal Disorders
SIZE & FINANCIALS
Employees:51-200
Ownership:private
Status:operating
FUNDING
Stage:Series B
Total Raised:$141M
Investors:Schroders, Atlas Venture, Forbion, Sofinnova Partners, Longwood Fund, Amgen Ventures, Athos KG, CDP Venture Capital, Columbia IMC, Neva SGR, Sixty Degree Capital, Willett Advisors, XGen Venture
PIPELINE
Stage:Phase 1/2
Lead Drug Stage:Phase 1/2
Modalities:Gene therapy, AAV vector platform
Active Trials:1
Trial Phases:Phase 1: 1 | Phase 2: 1
FDA Approvals:0
EMA Approvals:0
CORPORATE STRUCTURE
Key Partnerships:Telethon Institute of Genetics and Medicine (TIGEM), University of Naples Federico II
COMPETITION
Position:Emerging
Competitors:Nanoscope Therapeutics, Akouos, Adverum Biotechnologies
LEADERSHIP
Key Executives:
Natalia Misciattelli - CEO
Alberto Auricchio - Founder and Chief Science Officer
Philip Lao - SVP, Business Development
Scientific Founders:Alberto Auricchio
Board Members:Michael Heffernan (Chairman)
LINKS
Website:aavantgarde.com
LinkedIn:LinkedIn Profile
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